077 Cicatricial bullous pemphigoid and sjogren's syndrome: Case report in an elderly female
نویسندگان
چکیده
This case discusses the management of an 83-year-old female patient from Lebanon with Sjogren's Syndrome and Cicatricial Bullous Pemphigoid. The presented in January 2021 to internal medicine clinic for evaluation on off pruritic, burning blisters lower abdomen pubic area. She has hypothyroidism a 40 year long history difficulty exhaling through her nose. Family social unremarkable except using 2-5 cigarettes per day years. Her groin symptoms started spring 2019 by June 2020 developed sporadic pruritic non-pruritic rashes other locations progressive eye tearing redness. Upon primary care visit, she was being treated antibiotic steroid drops. taking oral antibiotics intermittently before U.S. began. labs were consistent staph aureus COPD so prescribed doxycycline later topical steroids, but lesions persisted. In consulted ENT increased breathing nose, who referred rheumatology because inflammation seen scope. diagnosed Sjorgen’s May (positive SS-A Abs speckled ANA) hydroxychloroquine 200mg plus prednisone 10mg daily. ophthalmology March redness watering informed that makes it impossible open tear ducts both eyes. same dermatologist suspected cicatricial bullous pemphigoid, given ocular dermatologic findings. A positive biopsy prompted switching HCQ 6-mercaptopurine 25mg then 50mg. patient's resolved quickly presence allergic type rash elevated liver enzymes soon afterwards daughter stop 6-MCP while continuing steroids. currently denies skin nose complaints remain. recommends rituximab cyclophosphamide, not them possible side effects.
منابع مشابه
Localized genital bullous pemphigoid; A case report
Bullous pemphigoid (BP) is an autoimmune bullous disorder with urticarial pruritic papules and plaques and tense bullae in flexural surfaces of body. The localized form of the disease is a rare variant which can be triggered by different stimuli. Hereunder, we report a patient with the local type involving genitalia without any triggering factors.
متن کاملMethotrexate Induced Bullous Pemphigoid: a Case Report
Background: Bullous pemphigoid (BP) is an autoimmune cutaneous blistering disorder. The precise precipitating etiology is not clear. There has been documented Drug-induced BP in case reports. Case report: We describe a case of a 44year old female with a past medical history of Psoriasis, who developed bullous pemphigoid. She had previously been on maintenance dose of 10mg intravenous methotrexa...
متن کاملOcular cicatricial pemphigoid masquerading as chronic conjunctivitis: a case report
Conjunctivitis is often considered an innocuous condition which is self-limiting. This report describes misdiagnosis of ocular cicatricial pemphigoid as chronic conjunctivitis. Ocular cicatricial pemphigoid is a rare autoimmune condition. The clinical features which are useful to distinguish this condition from infective conjunctivitis are discussed. The investigation and treatment of ocular ci...
متن کاملA recalcitrant case of cicatricial pemphigoid.
A 57-year-old woman presented with a 1-year history of blisters and erosions on her oral mucosa with bilateral conjunctivitis and symblephara formation. A diagnosis of cicatricial pemphigoid was made based on the clinical features and immunohistological findings. A multidisciplinary team managed her with different topical and systemic immunosuppressive agents but she finally succumbed due to mu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2023
ISSN: ['1523-1747', '0022-202X']
DOI: https://doi.org/10.1016/j.jid.2023.03.078